well HHS original and its remake have the cat TF(have to buy it using the weird dot things) and BE(rare seen where it mentions that the girls average bust size has increased thanks to the drugs you put in the school food). (lots of mind alterations)
HHS2 and its remake have mostly general Mind alterations with Futa options both had plans for more and were abandoned
HHS+ is the active one and they are working on the Cat TF and Futa drugs. BE drug is there in game just hard to make (like 75 chem skill out of 100)
the forum I will post after this post has the developers stuff and help sections and bug reports for HHS+ & HHS2 remake and the source work for HHS+ was gonna be a separate game but the main author disappeared
Code:
http://www.henthighschool.com/index.php